Synonyms

ALS22; TUBA1; H2-ALPHA; α-Tubulin

Background                                                       

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and arecomposed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Cross-Reactivity

Human, Mouse, Rat

Applications

WB, IF, ICC

Isotype

IgG

Immunogen

This information is considered to be commercially sensitive.

Storage Conditions

Store the Antibody at -20ºC and Primary Antibody Dilution Buffer at 4ºC for up to one year. The Primary Antibody Dilution Buffer can be stored at -20ºC for lone-term storage, but freeze-thaw may result in slight turbidity and a small amount of insoluble substance.